Vetted study · Verified Jun 17, 2026
MDMA-Assisted Massed Prolonged Exposure for PTSD
● Recruiting nowMDMAPTSD
DoD-funded MDMA plus a two-week massed Prolonged Exposure protocol for service members and veterans.
This is an interventional study — the research team administers the treatment under a controlled, IRB-approved protocol. Participation never happens outside that protocol.
★ Featured study
Microdosing Vets
Are you a combat veteran who's microdosed?
An Ethics Approved CIIS study documenting veterans' microdosing experience. Combat veterans 21–50 with a PTSD diagnosis and prior microdosing experience are needed.
- Substance
- MDMA
- Status
- Recruiting now
- Conditions
- PTSD
- Who can join
- Service members & veterans
- Where
- Atlanta, GA
- Run by
- Emory University / UT Health San Antonio
- Registry ID
- NCT07288151 ↗
How to join this study
Call or email the study team directly. You do not go through Psychedelic Vets — we just make the door easier to find.
Syreese Fuller
✉patstudy@emory.eduJessica Maples-Keller, PhD
Emory Brain Health Center — Atlanta, Georgia
☎404-712-1035✉patstudy@emory.eduContact details as published by the sponsor, last verified 2026-05. People move on — if this doesn't reach anyone, check ClinicalTrials.gov.
What taking part involves
You may receive a placebo.Participants are randomly assigned and neither you nor the team knows which you got. That is what makes the result trustworthy — and it means joining is not the same as being treated.
200 spotsEstimated enrollment for the whole study, across every site.
Ages 21–70
Who can join
Listed as the research team wrote them. This is not a decision about you — only the study team can say whether you are eligible, and the only way to find out is to ask them.
What the study is looking for
- PTSD diagnosis as assessed by Clinician-Administered Posttraumatic Stress Scale for DSM-5 - Revised (CAPS-5-R).
- Able to speak and read English (due to standardization of outcome measures).
- Willing to sign a release for the investigators to communicate with their primary care or mental health providers if indicated.
- Able to swallow pills.
- Agree to have study visits video and/or audio recorded, including Experimental Session, assessments, and non-drug therapy sessions.
- Willing to provide a contact (relative, spouse, close friend, or another support person) who is willing and able to be contacted by the investigators.
- Agree to inform the investigators within 48 hours of any medical conditions and procedures.
- If able to become pregnant, must have a negative pregnancy test before study entry, at study entry, and before the Medicine Session. Must agree to use adequate birth control for a month before the Medicine session and through 10 days after the Medicine Session.
- Agree to the following lifestyle modifications: comply with requirements for fasting and refraining from certain medications before the Medicine Session, and not participating in any other interventional clinical trials during the duration of the study, are driven home or to a hotel after the Medicine Session, and commit to medication dosing, therapy, and study procedures
What would rule you out
- Are not able to give adequate informed consent.
- Have previously participated in a Multidisciplinary Association for Psychedelic Studies (MAPS) sponsored MDMA clinical trial.
- Have any current problem which, in the opinion of the investigator or study physician, might interfere with participation.
- Have hypersensitivity to any ingredient of the Investigational Medicinal Product (IMP).
- Upon review of medical or psychiatric history and psychiatric assessment, have any current or past diagnosis that would be considered a risk to participating in the study
- Requires ongoing psychiatric medication use with certain exceptions. Individuals may decide to taper psychiatric medications under the guidance of their local provider.
- Have a history of any medical condition that could make receiving MDMA dangerous because of increases in blood pressure and heart rate or any medical condition the study physician believes would pose a safety risk or interfere with the effects of the treatment. Any medical disorder judged by the investigator to significantly increase the risk of MDMA administration by any mechanism is exclusionary.
- Have any unstable medical condition that would interfere with participation.
- Have uncontrolled hypertension) documented on three separate occasions.
- Have Wolff-Parkinson-White syndrome or any other accessory pathway that has not been successfully eliminated by ablation.
- Have a history of ever having ventricular arrhythmia or any other abnormal heart rhythm that the study physician believes would pose a significant risk of participation.
- Have an abnormal finding on electrocardiogram
- Have a history of additional risk factors for Torsade de Pointes (e.g., heart failure, hypokalemia, family history of Long QT Syndrome).
- Require the use of concomitant medications that could impact the effects or safety of MDMA during the Medicine Session.
- Have symptomatic liver disease or significant liver enzyme elevations.
- Have a history of hyponatremia or hyperthermia.
- Weigh less than 48 kilograms (105 lbs.).
- Are pregnant or nursing
- Have engaged in ketamine-assisted therapy or used ketamine within 12 weeks of enrollment
Go to the official study page on ClinicalTrials.gov →
You enroll directly with the research team through their own official page and IRB-approved consent process. Psychedelic Vets does not run this study or collect any of your health information.
Why this listing is here. Every study in our directory is hand-reviewed against a published set of standards — recruiting or clearly marked, registered or run by a known institution, open to U.S. veterans, and research-only (never facilitation of obtaining any substance). See how we vet →
If you're in crisis, the Veterans Crisis Line is free, confidential, and available 24/7 — you don't have to be enrolled in VA care. Dial 988, then press 1, or text 838255.
Study data is sourced from ClinicalTrials.gov (U.S. National Library of Medicine) and verified university/nonprofit sources. This page is educational and is not medical advice or an endorsement. Details can change — always confirm on the official page above. ← Back to all studies
