Vetted study · Verified Jul 5, 2026

Ketamine in Severe Traumatic Brain Injury

● Recruiting nowKetamineTBI

Early-phase trial of ketamine in patients hospitalized with severe traumatic brain injury.

This is an interventional study — the research team administers the treatment under a controlled, IRB-approved protocol. Participation never happens outside that protocol.

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Substance
Ketamine
Status
Recruiting now
Conditions
TBI
Who can join
Adults 18+ with severe TBI
Where
Dallas, TX
Run by
UT Southwestern Medical Center
Registry ID
NCT06062628 ↗

How to join this study

Call or email the study team directly. You do not go through Psychedelic Vets — we just make the door easier to find.

Anna Bashmakov, D.O.
Parkland Memorial Hospital — Dallas, Texas
214/648-4827Anna.Bashmakov@UTSouthwestern.edu
Anna Bashmakov, D.O.
Parkland Memorial Hospital — Dallas, Texas
214-648-4827Anna.Bashmakov@UTSouthwestern.edu

Contact details as published by the sponsor, last verified 2026-01. People move on — if this doesn't reach anyone, check ClinicalTrials.gov.

What taking part involves

Everyone receives the treatment.Single group, no placebo arm — there is no chance of being assigned to a dummy.
10 spotsEstimated enrollment for the whole study, across every site.
Ages 18– 

A single dose of 0.5 mg/kg (actual body weight) of ketamine will be administered intravenously. Ketamine will be administered in addition to the patient's existing analgesia, sedation and other medicines as a part of their routine treatment.

Who can join

Listed as the research team wrote them. This is not a decision about you — only the study team can say whether you are eligible, and the only way to find out is to ask them.

What the study is looking for

  • Severe traumatic brain injury
  • Placement of intracranial monitor for measurement of intracranial pressure and brain tissue oxygenation
  • Age greater than or equal to 18 years

What would rule you out

  • Documented allergy to ketamine
  • Sinus tachycardia with sustained heart rate \>120
  • Any episode of non-sinus tachycardia
  • Documented history of schizophrenia
  • Systolic blood pressure \> 180, diastolic blood pressure \> 120
  • Documented episode(s) of ICP elevations \>25 mm Hg sustained greater than 5 minutes within 24 hours
  • Similar episodes as above of PbtO2 \<15 mmHg
  • Positive pregnancy test and/or is currently breast-feeding
Go to the official study page on ClinicalTrials.gov →

You enroll directly with the research team through their own official page and IRB-approved consent process. Psychedelic Vets does not run this study or collect any of your health information.

Why this listing is here. Every study in our directory is hand-reviewed against a published set of standards — recruiting or clearly marked, registered or run by a known institution, open to U.S. veterans, and research-only (never facilitation of obtaining any substance). See how we vet →
If you're in crisis, the Veterans Crisis Line is free, confidential, and available 24/7 — you don't have to be enrolled in VA care. Dial 988, then press 1, or text 838255.

Study data is sourced from ClinicalTrials.gov (U.S. National Library of Medicine) and verified university/nonprofit sources. This page is educational and is not medical advice or an endorsement. Details can change — always confirm on the official page above. ← Back to all studies

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